Genistein is a powerhouse ingredient in Hernuvin’s skincare line, known for its anti-inflammatory and anti-ageing properties. In this post, we’ll explore what genistein is, how it benefits your skin, and why it’s a cornerstone of our formulations.
Genistein is a naturally occurring compound that belongs to the class of isoflavones. It was first isolated in 1899 from the brooming plant Genista tinctoria, which is how it got its name. Genistein is widely distributed in the Fabaceae family and is found in various plants, including soybeans, fava beans, and kudzu. It exhibits oestrogen-like functions in mammals and has been recognised for its multiple biological effects, including antioxidant, anti-inflammatory, and anti-cancer activities.
Genistein offers a multitude of benefits for the skin, making it a valuable ingredient in skincare products:
- Anti-inflammatory: Genistein helps reduce inflammation, which is crucial for healing and soothing irritated skin. Its anti-inflammatory properties make it effective in treating conditions like acne and rosacea.
- Antioxidant: Genistein acts as a potent antioxidant, neutralising free radicals that can cause oxidative stress and damage to the skin. This helps in preventing premature ageing and maintaining healthy skin.
- Anti-ageing: Genistein promotes collagen synthesis and inhibits collagen breakdown, which helps in reducing the appearance of fine lines and wrinkles. It also improves skin elasticity and firmness, contributing to a more youthful appearance.
Genistein works through several mechanisms to deliver its skin benefits:
- Oestrogen-like activity: Genistein mimics the action of oestrogen by binding to oestrogen receptors, which helps in maintaining skin thickness and elasticity, particularly beneficial for postmenopausal women.
- Tyrosine kinase inhibition: It inhibits tyrosine kinases, enzymes involved in cell growth and proliferation, thereby reducing the risk of skin cancer and promoting healthy cell turnover.
- Collagen synthesis: Genistein stimulates the production of collagen and other extracellular matrix components, which are essential for skin structure and resilience.
In Hernuvin products, genistein is combined with other potent ingredients like retinol and SPF30 to enhance its effectiveness. This synergy ensures comprehensive skin care, addressing multiple concerns such as ageing, scarring, and sun protection.
Numerous studies have highlighted the efficacy of genistein in skincare:
- Anti-ageing benefits: A randomised, double-blind, placebo-controlled clinical trial demonstrated that a topical product containing genistein improved skin hydration, reduced wrinkles, and enhanced skin quality in postmenopausal women.
- Wound healing: Research has shown that genistein can accelerate wound healing by improving extracellular matrix remodelling and turnover, making it beneficial for scarred and burned skin.
- Photoprotection: Studies on rodents have indicated that genistein can reduce UV-induced skin damage and tumour formation, showcasing its potential as a protective agent against photodamage.